Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: Implications for COVID-19 pathogenesis and consequences

SK Patel; JA Juno; WS Lee; KM Wragg; PM Hogarth; SJ Kent; LM Burrell

Journal article

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: Implications for COVID-19 pathogenesis and consequences

SK Patel, JA Juno, WS Lee, KM Wragg, PM Hogarth, SJ Kent, LM Burrell

European Respiratory Journal | EUROPEAN RESPIRATORY SOC JOURNALS LTD | Published : 2021

DOI: 10.1183/13993003.03730-2020

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Abstract

Plasma ACE2 activity is persistently elevated in patients after COVID-19 infection. Larger studies are needed to determine if this identifies people at risk of prolonged illness following COVID-19. https://bit.ly/2XQlrYF

University of Melbourne Researchers

Sheila Patel Author

Jennifer Juno Author

Wen Shi Lee Author

Kathleen Wragg Author

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Grants

Awarded by State Government of Victoria

Funding Acknowledgements

This study was supported by the Victorian Government (S.J. Kent, J.A. Juno), an Australian government Medical Research Future Fund award GNT2002073 (S.J. Kent, P.M. Hogarth), the ARC Centre of Excellence in Convergent Bio-Nano Science and Technology CE140100036 (S.J. Kent), NHMRC programme grants APP1149990 (S.J. Kent) and APP 1055214 (L.M. Burrell), project grant GNT1145303 (P.M. Hogarth), Medical Research Future Fund award GNT 1175865 (S.K. Patel, L.M. Burrell), Austin Medical Research Foundation Grant (S.K. Patel, L. M. Burrell). J.A. Juno and S.J. Kent are supported by NHMRC fellowships. Funding information for this article has been deposited with the Crossref Funder Registry.